1. Paolo Cuschieri, married to Grazia NN, with issue.

1.1. Pietro Cuschieri, married 1766 Valletta to Maria Pavia (d/o Crispino Pavia, s/o Matteo and Apollonia and (m 1747 Valletta) to Nataliza Schembri d/o Giuseppe and Rosa), with issue.

1.1.1. Giuseppe Cuschieri, married 1790 Valletta  to Maria Schembri, with issue.

1.1.1.1. Paolo Cuschieri, married 1830 Valletta to Anna Attard, with issue.

1.1.1.1.1. Salvatore Cuschieri, married 1876 Valletta to Enziona Cutajar, with issue.

1.1.1.1.1.1. Carmelo Cuschieri, married 1902 Valletta to Giorgina Tonna, with issue.
1.1.1.1.1.1.1. Savior Cuschieri, married 1930 Sliema to Angela Galea, with issue.
1.1.1.1.1.1.1.1. Prof Fr Andrew Cuschieri LLD, K.St J, National Order of Bolivia., (1934-2004), dunm.
1.1.1.1.1.1.1.2. Mary Cuschieri, married NN. Casingena.
1.1.1.1.1.1.1.3. Margherita Cuschieri, married NN. Galea.
1.1.1.1.1.1.1.4. Prof Sir. Alfred Cuschieri MD Kt.Bach (UK). (1938-)., married 1966 to Marguerite Holley., with issue.

1.1.1.1.1.1.1.4.1. Daughter Cuschieri

1.1.1.1.1.1.1.4.2. Daughter Cuschieri.

1.1.1.1.1.1.1.4.3. Daughter Cuschieri.
1.1.1.1.1.1.1.5. Anthony Cuschieri.
1.1.1.1.1.1.1.6. Victoria Cuschieri, married NN. Galea.
1.1.1.1.1.1.1.7. Gloria Cuschieri.

1.2. Francesco Cuschieri, married 1762 Valletta to Anna Falzon, with issue.

1.2.1. Gio Maria Cuschieri, married 1779 Valletta to Anna Zahra.

1.2.2. Maria Cuschieri, married 1794 Valletta to Francesco Attard.

1.2.3. Rosa Cuschieri, married 1791 Valletta to Francesco Borg, with issue.

1.2.3.1. Maria Borg, married 1857 Valletta to Emanuele Debono.

1.2.3.2. Felice Borg, married 1824 Valletta to Maria Buhagiar.

1. Filippo Cuschieri, married to Anna N, with issue.

1.1. Tommaso Cuschieri, married 1727 Valletta to Maria Mifsud.

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